Cannabis and Psilocybin are two of the most popular and widely used psychoactive substances. While both have been used for centuries for recreational and medicinal purposes, there are notable differences between the two.
In this article, we will explore the similarities and differences between Cannabis and Psilocybin, including their effects, side effects, and legal status. Additionally, we will examine the potential therapeutic benefits of these substances and their role in society today.
Whether you are a seasoned user or just starting to learn about these substances, this article will provide a comprehensive overview of Cannabis vs Psilocybin.
What is Cannabis?
Cannabis, also known as marijuana, is a psychoactive drug derived from the Cannabis plant. It is most commonly used for recreational and medicinal purposes and is known for its mind-altering effects, including feelings of relaxation, increased happiness, and altered perception of time and space.
Cannabis is typically consumed in various forms, including dried flowers (buds), edibles, tinctures, and oils. The legal status of cannabis varies greatly around the world, with some countries allowing for its recreational and medicinal use, while others have prohibited its use altogether
Chemical Composition of Cannabis
Cannabis contains over 100 different compounds, including the two most well-known and studied compounds: tetrahydrocannabinol or THC (C21H30O2) and cannabidiol or CBD (C21H30O2). THC is the psychoactive compound that is responsible for the “high” associated with marijuana use, while CBD is non-psychoactive and has a range of therapeutic effects.
What is Psilocybin?
Psilocybin is a naturally occurring psychoactive compound found in certain species of mushrooms, commonly referred to as “magic mushrooms”. It is most commonly used for recreational purposes, and is known for inducing profound changes in perception, thought, and mood.
When consumed, psilocybin is converted into psilocin, which is responsible for its psychoactive effects. Psilocybin is known to produce vivid and sometimes intense visual and auditory hallucinations, as well as changes in thought patterns and emotions.
It is also being studied for its potential therapeutic benefits, particularly in the treatment of depression, anxiety, and post-traumatic stress disorder (PTSD). Psilocybin is typically consumed in dried mushroom form, though it can also be found in capsule or liquid extract form.
Chemical Composition of Psilocybin
Psilocybin is a tryptamine alkaloid, which is a type of chemical compound found in a variety of species of fungi. The chemical structure of psilocybin consists of an indole ring, which is a type of organic ring structure, and a phosphate group.
It is chemically similar to the neurotransmitter serotonin, which is involved in regulating mood, appetite, and other bodily functions. When psilocybin is consumed, it is rapidly metabolized in the body into psilocin (C12H16N2O), which is the compound responsible for its psychoactive effects.
Cannabis vs. Psilocybin: Fact Sheet
| Cannabis | Psilocybin | |
|---|---|---|
| Generic Name | Hash | Magic Mushrooms |
| Drug Type | Psychoactive | Psychedelic |
| Active Ingredients | THC (C21H30O2) and CBD (C21H30O2) | Psilocin (C12H16N2O) |
| Used as treatment for: | Side effects of chemotherapy and AIDA | None but in studies for depression and PTSD |
| Available Form(s) | Dried Flowers Extract |
Dried Mushrooms Tablets |
| Is it a controlled substance? | Yes, Schedule I | Yes, Schedule I |
| Legal Status | Illegal | Illegal |
| Risk of Withdrawal Effects | Yes | Yes |
| Risk of Addiction | Low But Yes | Yes |
Psilocybin Dosage and Side Effects:
The effects of psilocybin are dose-dependent, meaning that the severity of the experience can vary depending on the amount consumed. The average dose of psilocybin is around 1-2 grams of dried mushrooms.
However, this can vary depending on the potency of the mushrooms, which can vary greatly. It is important to start with a low dose and work your way up, as a high dose can lead to intense and potentially overwhelming effects.
Common side effects of psilocybin use include nausea, headache, dizziness, and confusion. These side effects are generally mild and temporary, but they can be more severe in some individuals. In high doses, psilocybin can cause intense hallucinations and changes in perception that can be disorienting and potentially dangerous.
It’s also important to note that some individuals may have a bad trip, which can result in feelings of anxiety, paranoia, and fear. These effects can be particularly intense for individuals with a history of mental health problems or for those who take the substance in an unfamiliar or stressful environment.
Long-term effects of psilocybin use are not well understood, but there have been some studies suggesting that repeated use may lead to a decrease in the efficacy of the substance and an increased risk of adverse effects.
Cannabis Dosage and Side Effects:
The appropriate dose of cannabis can vary greatly depending on the method of consumption, the potency of the product, and the individual’s tolerance and experience with the substance. For smoking or vaporizing cannabis, a typical dose is 1-3 inhalations. For edibles, a dose can range from 5-10 milligrams of THC, with effects that can last for several hours.
It is important to start with a low dose and gradually increase to avoid overconsumption and adverse effects. It is also important to keep in mind that the effects of edibles can take longer to onset, but they can also last longer than other forms of consumption.
Common side effects of cannabis use include dry mouth, red eyes, increased heart rate, and impaired coordination and reaction time. These side effects are generally mild and temporary, but they can be more severe in some individuals.
In high doses, cannabis can cause intense hallucinations, paranoia, and anxiety. These effects can be particularly intense for individuals with a history of mental health problems or for those who take the substance in an unfamiliar or stressful environment.
Long-term effects of cannabis use are not well understood, but there have been some studies suggesting that repeated use may lead to a decrease in cognitive function, memory, and attention, and an increased risk of mental health problems, such as depression and anxiety.
Psilocybin vs. Cannabis: Can You Withdrawal for Either?
Yes it is possible to experience the withdrawal symptoms due to both psilocybin and cannabis use. However, the severity and duration of withdrawal symptoms can vary greatly between individuals and between substances.
Although psilocybin is not considered to be physically addictive, some individuals who use it regularly may experience mild withdrawal symptoms when they are trying to get off psilocybin. These symptoms can include anxiety, irritability, insomnia, and decreased appetite.
Cannabis is considered to be a mild to moderate substance of abuse and individuals who use it regularly may experience withdrawal symptoms when they stop using the substance. These symptoms can include irritability, anxiety, insomnia, decreased appetite, and physical symptoms such as sweating, chills, and headache.
It is important to keep in mind that withdrawal symptoms can vary greatly depending on the individual, the frequency and duration of use, and the amount used. If you are concerned about your substance use and are experiencing withdrawal symptoms, it is important to speak with a healthcare professional for guidance and support.
Cannabis vs Psilocybin: Prevalence in the United States
Both cannabis and psilocybin are used by people in the United States for recreational purposes, cannabis is much more widely available and used due to its legalization and decriminalization in many states, whereas psilocybin is still illegal for the majority of the country and its use is more limited.
According to the National Survey on Drug Use and Health (NSDUH), in 2020, approximately 45 million people aged 12 or older reported using cannabis in the past year, and 22 million reported using it in the past month. This represents a significant increase from previous years, likely due in part to the growing number of states that have legalized cannabis for medicinal or recreational use.
The same survey indicated that approximately 22.8 million individuals aged 12 or older (8.5% of the population) have used psilocybin at least once in their lifetime. Recent studies suggest that the use of psilocybin and other psychedelics is becoming more widespread, particularly among young adults.
Bottom Line: Cannabis versus Psilocybin
\While both substances have potential therapeutic benefits, they also come with risks and side effects. Many states have legalized cannabis, whereas psilocybin remains illegal in most of the country and has a limited use.
However, there is growing interest in the use of psilocybin for therapeutic purposes, and the decriminalization of psilocybin in some cities and states signals a shift in attitudes towards psychedelics.
The future of psychedelics is a topic of much discussion and speculation, but one thing is clear: the study and use of psilocybin and other psychedelics will continue to evolve and expand, as researchers and individuals alike seek to understand the true potential of these substances.
FAQs on Psilocybin and Cannabis
Psilocybin vs Cannabis: Which is more addictive?
Cannabis, in particular, can be habit-forming for some people and long-term use can lead to the development of a substance use disorder. On the other hand, there have been very few reported cases of psilocybin addiction, and it is not considered to be a habit-forming substance.
Is it possible to overdose on Cannabis?
While it is possible to consume too much cannabis, it is extremely rare for it to result in a fatal overdose. Cannabis works by interacting with the body’s endocannabinoid system, and while high doses can produce unwanted side effects such as anxiety, paranoia, and rapid heartbeat, they are not typically life-threatening.
However consuming it in combination with drugs like MDMA, alcohol or opioids can lead to severe side effects.
How many states in the USA have legalized recreational use of cannabis?
As of 2023, about 21 states in the USA have legalized the recreational use of cannabis.
