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Methamphetamine Overdose | Can I overdose on Methamphetamine?

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Methamphetamine, also known as “meth,” is a highly addictive and dangerous drug that can have severe consequences when misused. One of the most serious risks associated with meth use is the possibility of overdose. 

In this blog, we will explore the signs and symptoms of a methamphetamine overdose and discuss what steps to take if you or someone you know may be experiencing one. It is important to note that meth overdose can be fatal if not treated promptly, so it is crucial to understand the risks and take action if necessary.

What Does Methamphetamine Do? 

Methamphetamine, also known as “meth,” is a highly addictive stimulant drug that affects the central nervous system. When used, meth increases the levels of certain chemicals in the brain, such as dopamine and norepinephrine. This leads to increased energy, alertness, and euphoria. 

However, it can also lead to a host of adverse side effects, such as increased heart rate and blood pressure, anxiety, paranoia, and even psychosis. Long-term use of meth can cause damage to the brain, heart, and other organs, leading to addiction, overdose, and death.

Can you overdose on Methamphetamine? 

Yes, it is possible to overdose on methamphetamine. An overdose occurs when a person takes a dangerous or excessive amount of a substance, and in the case of meth, it can lead to serious health complications or even death. 

Methamphetamine causes an increase in the levels of certain chemicals in the brain, such as dopamine and norepinephrine. These chemicals are responsible for the drug’s euphoric effects, but when consumed in large amounts, it can cause a flood of these chemicals in the brain leading to a dangerous imbalance. 

High doses of meth can also lead to an increase in heart rate and blood pressure, which can cause damage to the heart and blood vessels over time. Additionally, meth can cause hyperthermia, a dangerous elevation of body temperature, which can lead to organ damage, seizures, and even death. 

Long-term use of meth can also cause changes in the brain that result in addiction, which can lead to compulsive drug-seeking behavior and an increased risk of overdose.

Normal dosage vs. lethal dosage?

A normal therapeutic dosage of methamphetamine for treating conditions such as ADHD is usually around 5-20 mg per day. However, this dosage should only be administered and monitored by a medical professional.

On the other hand, a lethal dosage of methamphetamine varies depending on several factors such as body weight, tolerance, and method of consumption. However, it is generally considered that a dose of around 50 mg or higher can be fatal for an average adult.

It is important to note that even small doses of meth can lead to serious health complications and long-term damage, so it is not recommended to use the drug recreationally or without medical supervision. Additionally, tolerance to the drug can build up quickly, which can lead users to take more and more of the drug, increasing the risk of overdose.

It’s important to mention that a lethal overdose of methamphetamine can be caused by a combination of factors, not just the amount of the drug consumed. Some of these factors can be the person’s medical history, any other substances used in combination, and underlying health conditions.

Symptoms of a Methamphetamine overdose

A methamphetamine overdose can have serious and even life-threatening consequences. The signs and symptoms of a meth overdose can vary depending on the amount of drug taken, the individual’s tolerance, and underlying health conditions. It’s important to be aware of the symptoms so that immediate medical attention can be sought if necessary.

Symptoms of a meth overdose can include:

  • Rapid heartbeat
  • High blood pressure
  • Chest pain
  • Agitation and aggression
  • Paranoia and hallucinations
  • Confusion and disorientation
  • Seizures
  • Stroke
  • Hyperthermia (elevated body temperature)
  • Coma
  • Cardiac arrest

It’s important to seek medical attention immediately if you suspect that you or someone else is experiencing a methamphetamine overdose. The sooner the person receives treatment, the better the chance of recovery.

What to do in case of Methamphetamine overdose?

If you suspect that someone has overdosed on methamphetamine, it is crucial to seek medical attention immediately. Time is of the essence in an overdose situation, and prompt treatment can greatly improve the chances of survival. Here are some steps to take in case of a meth overdose:

  • Call 911 or your local emergency number for an ambulance. Explain to the operator that you suspect a meth overdose.
  • If possible, try to stay with the person and keep them conscious and breathing.
  • If the person is unconscious or having seizures, try to protect their airway and keep them on their side to prevent choking.
  • If the person stops breathing or their heart stops, perform CPR if you know how.
  • Do not try to induce vomiting as it can be dangerous and cause more harm.
  • Do not hesitate to give as much information as possible to the emergency team when they arrive, including the amount of meth used and how it was consumed.
  • If the person survives the overdose, they will likely need further medical treatment and support for addiction.

It’s important to note that an overdose is a medical emergency and requires immediate attention, so it’s crucial not to hesitate in seeking help. Additionally, it’s important to understand that a meth overdose is not only a one-time event, but it can also have long-term consequences, and the person may need ongoing medical and behavioral treatment to fully recover.

Who is at risk of Methamphetamine overdose? 

Anyone who uses methamphetamine is at risk of overdose, but some individuals may be more vulnerable than others. The following groups of people may be at higher risk of meth overdose:

  • People who use high doses of meth.
  • People who have a history of drug abuse or addiction.
  • People who have a pre-existing medical condition such as heart disease, high blood pressure, or diabetes.
  • People mix meth with other drugs such as alcohol, opioids, or prescription medications.
  • For people  who use meth intravenously (injected into a vein) the risk of overdose is higher with this method of use.
  • People who use meth in an impure form, as it may contain other dangerous chemicals.
  • People who are new to meth use and don’t know their tolerance level.
  • People who have recently stopped using meth have a lower tolerance.

It’s important to note that anyone who uses meth is at risk of overdose and that it can happen to anyone regardless of the amount of meth consumed or the frequency of use. Also, people who are recovering from meth addiction may have a higher risk of overdose if they relapse and use meth again.

Can Methamphetamine interact with other drugs? 

Yes, methamphetamine can interact with other drugs, and the combination can be dangerous and even deadly. Methamphetamine is a powerful stimulant, and when combined with other substances, it can cause a dangerous increase in heart rate, blood pressure, and body temperature. This can lead to an increased risk of stroke, heart attack, and seizures. Mixing meth with other drugs can also increase the risk of overdose and death.

Some specific examples of dangerous drug interactions with meth include:

  • Combining meth with opioids, such as heroin or prescription painkillers, can increase the risk of respiratory failure and overdose.
  • Taking meth with antidepressants, such as SSRIs, can increase the risk of serotonin syndrome, a potentially fatal condition.
  • Mixing meth with nicotine or alcohol can increase the risk of liver damage and other organ damage.
  • Combining meth with cocaine can lead to severe hypertension (high blood pressure) and an increased risk of heart attack or stroke.

It’s important to note that mixing meth with any other drugs, prescription or not, can be dangerous and unpredictable. It is always best to avoid using any substances in combination with meth and to seek medical attention if you or someone you know has taken a combination of drugs.

How is Methamphetamine overdose treated? 

Treatment for a methamphetamine overdose typically begins with emergency medical care. The primary goal of treatment is to stabilize the person’s vital signs and manage any immediate symptoms or complications. Depending on the severity of the overdose, treatment may include:

  • Oxygen therapy: to help the person breathe and prevent brain damage from lack of oxygen.
  • Intravenous fluids: to help prevent dehydration and organ damage.
  • Medications: such as diazepam (Valium) to control seizures, and beta-blockers to lower blood pressure and heart rate.
  • Cooling blankets or ice packs: to lower body temperature if hyperthermia is present.
  • Medications to treat psychosis and agitation such as antipsychotics.

If the person survives the overdose, they will likely need further medical treatment and support for addiction. Medications-assisted treatment (MAT) such as methadone or buprenorphine, can help with the methamphetamine withdrawal symptoms, and behavioral therapy can help address the underlying psychological and social issues associated with meth addiction.

It’s important to note that treatment for meth addiction is a long-term process and requires a comprehensive approach that addresses the person’s physical, psychological, and social needs. 

Also, it’s important to understand that the risk of overdose doesn’t end once the person is stabilized, continuous care and follow-up are necessary to prevent relapse and overdose.

Final thoughts on Methamphetamine overdose

In conclusion, methamphetamine overdose is a serious public health issue that can have severe consequences for those who suffer from it. The drug’s highly addictive nature and the ease with which it can be manufactured and distributed make it a significant problem in many communities. 

It is important for individuals to be aware of the signs and symptoms of a methamphetamine overdose, and to seek medical attention immediately if they suspect someone may be experiencing one. 

Additionally, it is crucial for society to continue to support and fund research and treatment programs to help those struggling with addiction to methamphetamine, as well as to work to prevent its spread.


Warren Phillips

Warren is a Licensed Master Social Worker, who specializes in substance abuse and mental health treatment. Clinically, Warren has developed a therapeutic skillset that utilizes a strengths-based perspective, Twelve Step philosophies, Cognitive Behavioral Therapy and Motivational Interviewing.

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Charleston South Carolina

Located on the historic peninsula of Charleston, South Carolina, Lantana Recovery takes a modern approach to Substance Use Disorder treatment, offering intensive clinical care while also immersing our clients in local Charleston culture.